Table frontiersin Table 3D Perfusion volumetric and scoring table. Figure 4 frontiersin Figure 4. Tumor volume before and after treatment with neoadjuvant NABPLAGEM-NEO 2017. Patients who received a pre-treatment volume of 0 cc had stent involvement causing issues with the estimation of the tumor size. Cases with 0 cc post-treatment either had stent involvement or received surgery during the clinical trial. Refer to Table 2. Out of the 22 patients, 18 received a baseline R score of 5 or less, deeming them potential surgical candidates. There were nine unknown baseline tumor volumes due to the presence of stents. After treatment, 18 patients were considered resectable, and 13 patients proceeded with surgery.
Of the neoadjuvant therapy outcomes on tumor volume and R score, respectively. Figure 5 frontiersin Figure 5. R scores before and after treatment. Patients who Spain phone number list received a baseline R score of 0 had visible tumors with no vessel involvement. Those who received a final R score of 0 either had no vessel involvement, no visible tumor, or missing images or proceeded to surgery before the end of the study. Negative responses to treatment were recorded when there was no shrinkage in tumor volume and an elevated perfusion rate. Mild progression was seen in patient 26 (Figure 6), where the tumor volume pre-treatment was 10 cc and post-treatment was.
This slight increase in size suggested that the therapy was not doing well, and the patient was moved to surgery before the cancer could progress further since this patient had a stent and took longer to edit and quantify the tumor volume. Figure 6 frontiersin Figure 6. Patient 26 CT images for volumetric and perfusion analysis. Arterial (a, d) and venous phases (b, e) were used to develop the 3D analysis (c, f) of the patient's tumor. The patient's pre-treated tumor volume was estimated at 10 cc and the post-treated tumor volume was 12 cc. However, no change in the R score was observed from a baseline score of 1 to a final score of 1. Even though the tumor size was increasing, the patient still qualified for surgery due to low vascular invasion.